Hyperthermia Chemo-sensitization, Chemical Thermo-sensitization and Apoptosis
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چکیده
منابع مشابه
Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradation and sensitization to radiation by hyperthermia.
Hyperthermia can transiently degrade BRCA2 and thereby inhibit the homologous recombination pathway. Induced DNA-double strand breaks (DSB) then have to be repaired via the error prone non-homologous end-joining pathway. In the present study, to investigate the role of hyperthermia in genotoxicity and radiosensitization, the induction of chromosomal aberrations was examined by premature chromos...
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ژورنال
عنوان ژورنال: Thermal Medicine
سال: 2008
ISSN: 1882-2576,1882-3750
DOI: 10.3191/thermalmed.24.1